Condition / reason: glaucoma Dosage duration: one drop (dosage frequency: once daily) for the period of 3 months Other conditions: none Other drugs taken: none Reported Results Benefits: reduce elevated pressure in the eyes and relieve hypertension.My eye pressure was in the mid 20 s.
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To provide baseline comparison data, all patients were placed on timolol maleate 0.5 (one drop in each eye twice each day) for a period of 6 weeks. To be eligible for randomization, a mean diurnal IOP 19 mmHg, under treatment with timolol 0.5 BID, was required.Study visits occurred at baseline and after 6 and 12 weeks of therapy. The masked investigator performed three IOP measurements in each eye, alternating between eyes, and starting with the right eye at 0800, 1000, 1200, 1400, 1600, 1800, and 2000 hours. Antonio Martnez has received honoraria from lectures and reimbursement for attending symposia from Allergan. Financial interest: None Top of page Introduction. Lowering intraocular pressure (IOP) reduces the risk of visual field loss in patients with glaucoma and ocular hypertension.
The mean of these three measurements at each time point was used in the statistical analyses. Table 1 summarizes the main inclusion and exclusion criteria. Table 1 - Inclusion/exclusion criteria. Full table Methods The methods of this study were similar to those described previously by.1, 2, 3 Whenever possible, it is preferable to control IOP with a single drug rather than multiple drugs, because every drug added to the regime has side effects, and each added drug increases the costs and may reduce patient compliance.
When a single medication does not adequately reduce IOP, additional hypotensive agents are added to the therapeutic regime. In this setting, a fixed combination preparation may improve both the compliance and the quality of life.5, 6, 7, 8, 9, 10, 11, 12, 13 The fixed combination bimatoprost/timolol (BTFC ; Ganfort, Allergan, Irvine, CA) is a new fixed combination antiglaucoma therapy that combines bimatoprost 0.03 and timolol 0.5.
4 The fixed combination of latanoprost and timolol (LTFC ; Xalacom, Pharmacia, Kalamazoo, MI, and Pfizer, New York, NY) was the first prostaglandin analogue/beta-blocker fixed combination available in the market. Several papers have shown the IOP-lowering effect of the LTFC.15 Our study found that BTFC demonstrated a superior IOP-lowering effect than LTFC in OAG patients over a period of 4 weeks. The purpose of this study was to evaluate the 12-h pressure curve of BTFC vs LTFC, both administered in the evening in patients.
To the best of our knowledge (after a Medline search, update December 2007 this is the first crossover study to compare 12-h diurnal IOP reduction with these two fixed combinations. Top of page.For entry into the study, the IOP-lowering effect of prostaglandin analogues must be higher than 20. Glaucoma was defined on the basis of at least two reliable achromatic automated perimetry using the 24-2 Swedish Interactive Threshold Algorithm (SITA ) (Humphrey visual field analyzer, Carl Zeiss.
Patients Enrolled patients were men or women of at least 40 years with a clinical diagnosis of OAG, with or without exfoliation syndrome. The study was conducted on consecutive patients, referred or recruited, attending the outpatient service of the Glaucoma Unit, Instituto Galego de Oftalmoloxia.All patients signed a written informed consent form in accordance with the tenets of the Declaration of Helsinki and with local ethical approval. We included patients of either gender, older than 40 years, who had an IOP of 19 mmHg, under treatment with prostaglandin analogues, at.
17 At the screening visit (visit(An applicator is not supplied but a very fine eyeliner brush is suitable) Do not apply to the lower lid. Also avoid touching other areas with Lumigan eye drops, as this may result in unwanted hair growth.
2011 May. 129(5 562-8. Medline. Rao HL, Kumar AU, Babu JG, Senthil S, Garudadri CS. Relationship between Severity of Visual Field Loss at Presentation and Rate of Visual Field Progression in Glaucoma.And removing it at night gives a rest to your lashes. The same rule applies here to your eye lashes as your skin as they are both equally delicate. Also, be very gentle when you are removing your eye makeup.
Ask your doctor or pharmacist for more information. Bimatoprost Precautions Back to Top Bimatoprost may turn the iris (the colored part of the eye) brown. This change may be permanent. Bimatoprost may also darken the eyelid skin, and cause eyelashes to grow longer and thicker.
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