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How is LATISSE used? LATISSE solution is a once-daily prescription treatment applied to the base of the upper eyelashes with a sterile, single-use-per-eye disposable applicator. LATISSE should not be applied to the lower eyelashes as there is a potential for hair growth to occur in.
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Postmarketing reports indicate that the effects of BOTOX Cosmetic and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These may include asthenia, generalized muscle weakness, diplopia, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence and breathing. Use caution when administering to patients with pre-existing cardiovascular disease. Pre-existing Neuromuscular Disorders Individuals with peripheral motor neuropathic diseases, amyotrophic lateral sclerosis, or neuromuscular junction disorders (eg, myasthenia gravis or Lambert-Eaton syndrome) should be monitored when given botulinum toxin.
Please See Full LATISSE Product Information (PDF) LATISSE Web site.
These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults treated.
LATISSE use may cause darkening of the eyelid skin which may be reversible. Although not reported in clinical studies, LATISSE use may also cause increased brown pigmentation of the colored part of the eye which is likely to be permanent.
These include skin darkening, eye irritation, dryness of the eyes, and redness of the eyelids. If you develop a new ocular condition (e.g., trauma or infection experience a sudden decrease in visual acuity, have ocular surgery, or develop any ocular reactions, particularly conjunctivitis and eyelid.
If use of LATISSE is discontinued, eyelashes will gradually return to where they were prior to treatment over a period of weeks to months (average eyelash hair cycle). Ask your doctor if LATISSE is right for you.
Human Albumin and Transmission of Viral Diseases This product contains albumin, a derivative of human blood. Based on effective donor screening and product manufacturing processes, it carries an extremely remote risk for transmission of viral diseases.
Cardiovascular System There have been reports following administration of BOTOX of adverse events involving the cardiovascular system, including arrhythmia and myocardial infarction, some with fatal outcomes. Some of these patients had risk factors including pre-existing cardiovascular disease.
Patients using prostaglandin analogs including. LUMIGAN for IOP reduction should only use. LATISSE after consulting with their physician and should be monitored for changes to their intraocular pressure. Increased iris pigmentation has occurred when bimatoprost solution was administered.
Use of anticholinergic drugs after administration of BOTOX Cosmetic may potentiate systemic anticholinergic effects. The effect of administering different botulinum neurotoxin products at the same time or within several months of each other is unknown.
In these cases, the adverse reactions were not necessarily related to distant spread of toxin, but may have resulted from the administration of BOTOX to the site of injection and/or adjacent structures.
USE IN SPECIFIC POPULATIONS BOTOX Cosmetic is not recommended for use in children or pregnant women. It is not known whether BOTOX Cosmetic is excreted in human milk. Caution should be exercised when BOTOX Cosmetic is administered to a nursing woman.
The most frequently reported adverse event following injection of BOTOX Cosmetic for lateral canthal lines was eyelid edema (1). DRUG INTERACTIONS Co-administration of BOTOX Cosmetic and aminoglycosides or other agents interfering with neuromuscular transmission (eg, curare-like compounds) should only be performed with caution as the.